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Search Results for " pfi 2 "

4

Compounds

Cat No. Product Name Synonyms Targets
T4583 PFI-2 hydrochloride (R)-PFI-2 hydrochloride,PFI-2 HCl Histone Methyltransferase
PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM), 500 fold active than (S)-PFI-2.
T1987 PFI-2 PFI2,PFI 2,(R)-PFI-2 Histone Methyltransferase
PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.
T6939 PFI-3 PFI 3 Epigenetic Reader Domain
PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.
T81175 SETD7-IN-1 Histone Methyltransferase
SETD7-IN-1 (compound 7), a PFI-2 analogue, acts as both a substrate and inhibitor of histone lysine methyltransferase SETD7, exhibiting an inhibitory concentration (IC50) of 0.96 ± 0.10 µM [1].
TargetMol